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. 2026 Jul 26;18(7):e113385. doi: 10.7759/cureus.113385

Table 13. Benchmarking of current study against major published series.

Literature benchmarks were derived from landmark studies including the Mayo Clinic Meckel’s diverticulum series, NANETS neuroendocrine tumor (NET) guidelines, European Society for Medical Oncology (ESMO) gastrointestinal stromal tumor (GIST) cohorts, and contemporary Crohn’s disease surgical studies.

Parameter Current study (n = 34) Mayo Clinic Meckel series (Park et al.) [20] NANETS midgut NET studies [21,22] ESMO/European GIST cohorts [23,24] Contemporary Crohn’s surgical cohorts [25-27]
Study population Uncommon surgically managed small intestinal disorders Meckel’s diverticulum Small bowel NETs GIST Crohn’s disease
Sample size 34 1,476 Large multicenter consensus datasets Multicenter European cohorts Large tertiary referral cohorts
Mean age (years) 46.7 ± 16.4 Predominantly adults 60–65 55–65 25–40
Male sex (%) 70.6% ~75% symptomatic cases 55–60% 50–60% 45–55%
Abdominal pain (%) 100% Variable Common Common Common
Obstruction (%) 44.1% Major adult presentation Frequent advanced presentation Less common Common
GI bleeding (%) 20.6% Most common symptomatic adult presentation May occur Rare Uncommon
Surgical treatment (%) 100% 100% resected cases Surgical resection cornerstone Complete surgical excision cornerstone Surgery for complicated disease
Recurrence (%) 5.9% Very low after resection Variable by stage 10–40% depending on risk 20–40% long-term
Overall morbidity (%) 11.8% Low 10–20% 10–25% 20–35%
Overall survival (%) 100% Favourable 5-year survival often >80–90% for localized disease Favorable after complete resection and adjuvant therapy Favorable but recurrent disease common