Table 1.

AMSTAR-2 quality rating

Quality of AMSTAR criteria
There are 7 critical items
AMSTAR-2 Item #	Description
2	Protocol registered
4	Comprehensive search strategy
7	Excluded studies listed with reasons
9	Risk of bias assessed for included studies
11	Appropriate statistical methods
13	Heterogeneity explained
15	Conflicts of interest disclosed
Rating	Criteria
□ High	No or 1 non-critical weakness
□ Moderate	More than 1 non-critical weakness, no critical flaws
□ Low	1 critical flaw, with or without non-critical weaknesses
□ Critically Low	> 1 critical flaw or major issues in protocol, methods, or bias handling