TABLE 1.
Inheritance of the lpa2 deletion allele
| Parental lpa2 genotypes | No. (%) of offspring with lpa2 genotypea
|
No. of −/− expected | ||
|---|---|---|---|---|
| +/+ | +/− | −/− | ||
| Wild-type background | ||||
| +/+ × +/− | 125 (52) | 115 (48) | 0 (0) | 0 |
| +/− × +/− | 52 (24) | 110 (51) | 53 (25) | 54 |
| +/− × −/− | 0 (0) | 133 (53) | 118 (47) | 133 |
| Ratio of sexes (female:male) | 90:85 | 188:170 | 96:93 | |
| lpa1(−/−) background | ||||
| +/− × +/− | 14 (27) | 29 (56) | 9 (17) | 14 |
| +/− × −/− | 0 (0) | 28 (57) | 21 (43) | 28 |
a
Numbers of individual progeny genotyped from the indicated crosses are shown. In parentheses is the percentage of each genotype from a particular cross. Tailing was done at weaning age (approximately 3 weeks).