Table 2.
Clinical information for the 82 patients used for RNA sequencing grouped according to Tfh cell infiltration.
| Clinical characteristic | Tfh-high (n=34) | Tfh-low (n=34) |
|---|---|---|
| Gender (Female) | 29/34 | 25/34 |
| Age | 49.18 ± 13.26 | 49.68 ± 15.51 |
| Xerostomia (%) | 85.3** | 52.9 |
| Xerophthalmia (%) | 61.8* | 35.3 |
| ANA+ (%) | 94.1* | 76.5 |
| RF (%) | 44.1** | 8.8 |
| Anti-SSA+ (%) | 79.4 | 55.9 |
| Anti-Ro52+(%) | 58.8 | 52.9 |
| Anti-SSB+ (%) | 26.5 | 20.6 |
| IgG (g/L) | 17.43 ± 6.00** | 13.30 ± 4.25 |
| IgA (g/L) | 3.01 ± 1.34 | 2.66 ± 1.08 |
| IgM (g/L) | 1.64 ± 1.04 | 1.41 ± 0.80 |
| C3 (g/L) | 1.08 ± 0.16 | 1.15 ± 0.22 |
| C4 (g/L) | 0.27 ± 0.09 | 0.32 ± 0.10 |
| Hypergammaglobulinaemia (%) | 44.1** | 14.7 |
| Hypocomplementemia (%) | 2.9 | 2.9 |
Data are mean ± standard deviation (SD) or n (%). *p<0.05; **p<0.01; ***p<0.001. ANA= anti-nucleic antibody. RF, rheumatoid factors.