| NK | Natural killer |
| TME | Tumor Microenvironment |
| ECM | Extracellular matrix |
| 3D | Three-dimensional |
| CLPs | Common lymphoid progenitors |
| ADCC | Antibody-dependent cellular cytotoxicity |
| KIR | Killer-cell Immunoglobulin-like Receptors |
| MHC-I | Major Histocompatibility Complex Class |
| FasL | Fas ligand |
| TNF | Tumor necrosis factor |
| TRAIL | TNF-related apoptosis-inducing ligand |
| DISC | Death-Inducing Signaling Complex |
| IL-2 | Interleukin 2 |
| IFN-α | Interferon-alpha |
| DCs | Dendritic cells |
| CSCs | Cancer Stem Cells |
| IFN-γ | Interferon-gamma |
| cDC1 | Conventional type 1 dendritic cells |
| Th1 | T-helper 1 |
| CTCs | Circulating tumor cells |
| CAFs | Cancer-associated fibroblasts |
| MDSCs | Myeloid-derived suppressor cells |
| Treg | Regulatory T cells |
| cNK | Circulating NK cells |
| TGF-β | Transforming growth factor-beta |
| hTERT | Human telomerase |
| trNK | Tissue-resident NK cells |
| EMT | Epithelial–mesenchymal transition |
| TAMs | Tumor-associated macrophages |
| PD-1 | Programmed Death-1 |
| HIF-1α | Hypoxia-Inducible Factor 1-alpha |
| VEGF | Vascular endothelial growth factor |
| ROS | Reactive oxygen species |
| MMPs | Matrix metalloproteinases |
| PGC-1α | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| LDH | Lactate dehydrogenase |
| ADAMs | A Disintegrin and Metalloproteinase |
| ADO | Adenosine |
| EV | Extracellular vesicle |
| 2D | Two-dimensional |
| PDO | Patients derived organoids |
| MTSs | Multicellular Tumor Spheroids |
| CAR | Chimeric antigen receptor |
| PEG | Polyethylene glycol |
| PLA | Polylactic acid |
| PLG | Poly lactide-co-glycolide |
| PLGA | Poly(lactic-co-glycolic acid) |
| OoC | Organ-on-chip |
| PDTOs | Patient-derived immunocompetent tumor organoids |
| ALI | Air-liquid interface |
| CIML | Cytokine-induced memory-like NK cells |