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. 2026 Jun 24;14(7):1427. doi: 10.3390/biomedicines14071427
ACLY ATP-citrate lyase.
AKT Protein kinase B.
AMPK Adenosine monophosphate-activated protein kinase.
Arg-1 Arginase 1.
ATF4 Activating transcription factor 4.
ATF6 Activating transcription factor 6.
Bax Bcl-2-associated X protein.
Bcl-2 B-cell lymphoma 2.
BCAA Branched-chain amino acid.
CHOP C/EBP homologous protein.
Cyt c Cytochrome c.
DAG Diacylglycerol.
DAMPs Damage-associated molecular patterns.
Drp1 Dynamin-related protein 1.
EGF/VEGF Epidermal growth factor/vascular endothelial growth factor.
eIF2α-P Phosphorylated eukaryotic initiation factor 2α.
ERS Endoplasmic reticulum stress.
ETC Electron transport chain.
FFA/NEFA Free fatty acid/non-esterified fatty acid.
FoxO1 Forkhead box protein O1.
G6Pase Glucose-6-phosphatase.
GLUT1 Glucose transporter 1.
GLUT4 Glucose transporter 4.
GLUTs Glucose transporters.
GPx-1 Glutathione peroxidase 1.
GRP75 Glucose-regulated protein 75.
GSH-Px Glutathione peroxidase.
HG High glucose.
HIF-1α Hypoxia-inducible factor 1-alpha.
HK2 Hexokinase 2.
HO-1 Heme oxygenase-1.
IL-1β Interleukin-1β.
IL-6 Interleukin-6.
iNOS Inducible nitric oxide synthase.
IP3R Inositol 1,4,5-trisphosphate receptor.
IRE1α Inositol-requiring enzyme 1α.
IRK Insulin receptor kinase.
IRS1/2 Insulin receptor substrate 1/2.
JNK c-Jun N-terminal kinases.
M1 Classically activated macrophage.
M2 Alternatively activated macrophage.
MAPK Mitogen-activated protein kinase.
MAMs Mitochondria-associated endoplasmic reticulum membranes.
MDA Malondialdehyde.
MFN1/2 Mitofusin 1/2.
mPTP Mitochondrial permeability transition pore.
mtDNA Mitochondrial DNA.
mtROS Mitochondrial reactive oxygen species.
mTOR Mechanistic target of rapamycin.
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells.
NLRP3 NLR family pyrin domain-containing 3.
NQO1 NADPH quinone oxidoreductase.
Nrf2 Nuclear factor erythroid 2-related factor 2.
NRF1/2 Nuclear respiratory factor 1/2.
OXPHOS Oxidative phosphorylation.
p38 p38 mitogen-activated protein kinase.
PEPCK Phosphoenolpyruvate carboxykinase.
PFK1 Phosphofructokinase 1.
PGC-1α Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
PHD Prolyl hydroxylase.
PI3K Phosphatidylinositol 3-kinase.
PKCθ Protein kinase C θ
PP2A Protein phosphatase 2A.
ROS Reactive oxygen species.
SCFA Short-chain fatty acid.
SERCA Sarco/endoplasmic reticulum calcium ATPase.
SIRT1 Sirtuin 1.
SOD Superoxide dismutase.
SOD-1 Superoxide dismutase 1.
T2DM Type 2 diabetes mellitus.
TCA cycle Tricarboxylic acid cycle.
TFAM Mitochondrial transcription factor A.
TLR4 Toll-like receptor 4.
TNF-α Tumor necrosis factor-α.
TRX Thioredoxin.
UCP2 Uncoupling protein 2.
VDAC Voltage-dependent anion channel.
XBP1 X-box binding protein 1.
XBP1s Spliced X-box binding protein 1.
ΔΨm Mitochondrial membrane potential.