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Algorithm 1 Offline Confidence-Gated Iterative Refinement |
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Require:
Training partition , validation partition ; initial primary system , verification system ; high-confidence threshold ; feedback scaling factor (empirically determined on ); maximum iterations ; early stopping tolerance
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Ensure:
Refined parameters ,
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Pre-train on (Adam optimiser, cosine annealing, early stop on validation )
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Pre-train on (stratified 5-fold cross-validation)
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for to T do
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Run fixed-weight inference with and over ; compute via Equation (19) for each x
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Construct refinement pool (curriculum gate):
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▹ Equivalent to dual-agreement; see Equation (19) with
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All cases with excluded from ; disagreement cases routed for clinician review
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Compute TreeSHAP attributions over ; aggregate and -normalise per feature to obtain
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FSG modulation via Equation (20): ; row-wise -normalise
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Freeze Mamba SSM and Bi-LSTM backbone; fine-tune FSG parameters () and classification head of on (ground-truth labels)
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Retrain on (ground-truth labels)
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Evaluate of on
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if and then
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break ▹ Early stopping: marginal AUC gain below convergence threshold
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end if
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end for
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return ,
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