APE	lung adenocarcinoma
AUC	area under the curve
BBB	blood–brain barrier
BC	Breast Cancer
ccRCC	clear-cell Renal Cell Carcinoma
cfNAs	cell-free nucleic acids
CRPC	castration-resistant prostate cancer
CTCs	circulating tumor cells
DNAM1	DNAX Accessory Molecule-1
dUC	differential Ultracentrifugation
DGC	Density Gradient Centrifugation
EGFR	epidermal growth factor receptor
EVs	Extracellular vesicles
EXPOs	exocyst-positive organelles
FFE	Free-Flow Electrophoresis
FFF	Field-Flow Fractionation
GMP	Good Manufacturing Practice
HCC	hepatocellular carcinoma
HEK293	human embryonic kidney cells
HIC	Hydrophobic interaction chromatography
HULC	Highly Upregulated in Liver Cancer
HUVECs	human umbilical vein endothelial cells
ISEV	International Society for Extracellular Vesicles
IL	Interleukin
lEVs	large extracellular vesicles
mEVs	milk-derived extracellular vesicles
MISEV	Minimal Information for Studies of Extracellular Vesicles
MRC-9	normal fibroblasts
MSCs	mesenchymal stem cells
NK	natural killer
NPE	benign pleural lesions
NSCLC	non-small cell lung cancer
PBS	phosphate-buffered saline
PCa	Prostate Cancer
PDEVs	Plant-derived extracellular vesicles
PD-L-1	Programmed Death-Ligand 1
pDMG	pediatric diffuse midline gliomas
PEG	Polyethylene glycol
pHGG	pediatric High-Grade Glioma
PTX	Paclitaxel
SCLC	small cell lung cancer
sEVs	small extracellular vesicles
SEC	Size Exclusion Chromatography
TFF	Tangential flow filtration
TfR	transferrin receptor
Ti-EVs	tumor Tissue Extracellular vesicles
TPE	pleural tuberculosis
uEVs	urine Extracellular vesicles