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. 2002 Dec;22(23):8204–8214. doi: 10.1128/MCB.22.23.8204-8214.2002

FIG. 7.

FIG. 7.

mtGPAT−/− mice have altered liver PE fatty acid composition. PE from mtGPAT+/+ and mtGPAT−/− mice (n = 6 per genotype) was separated from other liver phospholipids by solid-phase column chromatography. After methyl esterification, total PE fatty acids were quantified by GC. A portion of the PE fraction was digested with PLA2 and then subjected to acid hydrolysis. (A) Total fatty acids. (B) sn-1 fatty acids. (C) sn-1 fatty acid classes (Sat, saturated; Mono, monounsaturated; Poly, polyunsaturated). (D) sn-2 fatty acids. (E) sn-2 fatty acid classes. Only the major fatty acids are presented. a, P < 0.05; b, P < 0.005; c, P < 0.001.