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. 2026 Jul 16;16(7):1039. doi: 10.3390/biom16071039
ADAMTS A disintegrin and metalloproteinase with thrombospondin motifs
AKT Protein kinase B
AR Androgen receptor
ARG1 Arginase 1
ASPN Asporin
BGN Biglycan
BMP Bone morphogenetic protein
CAFs Cancer-associated fibroblasts
cAMP Cyclic adenosine monophosphate
CCL C-C motif chemokine ligand
CCR C-C motif chemokine receptor
CD Cluster of differentiation
CD1d Cluster of differentiation 1d
CD44 Cluster of differentiation 44
RHAMM/CD168 Receptor for hyaluronan-mediated motility
CREB cAMP response element-binding protein
CSF-1 Colony-stimulating factor 1
CSF-1R Colony-stimulating factor 1 receptor
CSPG4 Chondroitin sulfate proteoglycan 4
CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
CXCL C-X-C motif chemokine ligand
CXCR C-X-C motif chemokine receptor
DCN Decorin
DCs Dendritic cells
DNAM-1 DNAX accessory molecule 1
ECM Extracellular matrix
EGF Epidermal growth factor
EGFR Epidermal growth factor receptor
eIF4E3 Eukaryotic translation initiation factor 4E family member 3
EMT Epithelial–mesenchymal transition
ERBB2/HER2 Erb-b2 receptor tyrosine kinase 2/human epidermal growth factor receptor 2
ERK Extracellular signal-regulated kinase
FAK Focal adhesion kinase
FGF Fibroblast growth factor
FGFR Fibroblast growth factor receptor
FOXP3 Forkhead box P3
Gab1 GRB2-associated-binding protein 1
GAG Glycosaminoglycan
GDF10 Growth differentiation factor 10
GLI2 GLI family zinc finger 2
GPC3 Glypican-3
GPC6 Glypican-6
GPI Glycosylphosphatidylinositol
HA Hyaluronan
HAS2 Hyaluronan synthase 2
HGF Hepatocyte growth factor
HPSE Heparanase
HSPG Heparan sulfate proteoglycan
HSPG2 Heparan sulfate proteoglycan 2/perlecan
HSPGs Heparan sulfate proteoglycans
IFN-γ Interferon gamma
IGF Insulin-like growth factor
IGF1R Insulin-like growth factor 1 receptor
IL Interleukin
IL-8/CXCL8 Interleukin-8/C-X-C motif chemokine ligand 8
iNOS Inducible nitric oxide synthase
JAK Janus kinase
JNK C-Jun N-terminal kinase
LOX/LOXL2 Lysyl oxidase/lysyl oxidase-like 2
MAMs Metastasis-associated macrophages
MAPK Mitogen-activated protein kinase
MDSCs Myeloid-derived suppressor cells
MET Mesenchymal–epithelial transition factor receptor
MFG-E8 Milk fat globule-EGF factor 8
MHC Major histocompatibility complex
MMP Matrix metalloproteinase
MMP-7 Matrix metalloproteinase 7
MMPs Matrix metalloproteinases
NF-κB Nuclear factor kappa B
NG2 Neuron-glial antigen 2
NK cells Natural killer cells
NKT cells Natural killer T cells
NO Nitric oxide
OPG Osteoprotegerin
PD-1 Programmed cell death protein 1
PD-L1 Programmed death-ligand 1
PDGF Platelet-derived growth factor
PDGFR Platelet-derived growth factor receptor
PG Proteoglycan
PGE2 Prostaglandin E2
PI3K Phosphoinositide 3-kinase
PKA Protein kinase A
PKCα Protein kinase C alpha
PTHrP Parathyroid hormone-related protein
p38 MAPK p38 mitogen-activated protein kinase
RANK Receptor activator of nuclear factor-κB
RANKL Receptor activator of nuclear factor-κB ligand
RB Retinoblastoma protein
RHAMM Receptor for hyaluronan-mediated motility
Rho GTPase Rho guanosine triphosphatase
ROCK Rho-associated coiled-coil kinase
ROCK1 Rho-associated coiled-coil kinase 1
ROS Reactive oxygen species
RTK Receptor tyrosine kinase
scRNA-seq Single-cell RNA sequencing
SDC Syndecan
SDC1 Syndecan-1
SDC1/CD138 Syndecan-1/cluster of differentiation 138
Sema3A Semaphorin 3A
SHH Sonic hedgehog
SLRP Small leucine-rich proteoglycan
SMAD Suppressor of mothers against decapentaplegic proteins
Src Proto-oncogene tyrosine-protein kinase Src
SREs Skeletal-related events
SRGN Serglycin
STAT3 Signal transducer and activator of transcription 3
SULF1/2 Sulfatase 1/2
TAMs Tumor-associated macrophages
TANs Tumor-associated neutrophils
Tc17 IL-17-producing cytotoxic T cells
TGF-β Transforming growth factor beta
TGFβ-RIII Transforming growth factor beta receptor III/betaglycan
Th T helper cell
TLR Toll-like receptor
Tregs Regulatory T cells
VCAM-1 Vascular cell adhesion molecule 1
VCAN Versican
VEGFA Vascular endothelial growth factor A
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor
VEGFR2 Vascular endothelial growth factor receptor 2
WNT Wingless/integrated signaling pathway
WNT3A Wingless-type MMTV integration site family member 3A
YAP/TAZ Yes-associated protein/transcriptional coactivator with PDZ-binding motif
ZEB1 Zinc finger E-box-binding homeobox 1