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. 2026 Jul 6;16(7):991. doi: 10.3390/biom16070991
ADH5 alcohol dehydrogenase 5 (also known as GSNOR)
AGT O6-alkylguanine-DNA alkyltransferase (also known as MGMT)
ALDH aldehyde dehydrogenase
AMeD aplastic anemia, mental retardation and dwarfism syndrome
AML acute myeloid leukemia
APE1 apurinic/apyrimidinic endonuclease 1
ATM ataxia telangiectasia mutated
ATP13A3 adenosine triphosphatase 13A3
ATR ataxia telangiectasia and Rad3 related
53BP1 p53 binding protein 1
BRCA breast cancer gene
CHK1 checkpoint kinase 1
CNA copy number alteration
CRISPR clustered regularly interspaced short palindromic repeats
CSB Cockayne syndrome B protein
DDR DNA damage response
DNA-PKcs DNA-dependent protein kinase catalytic subunit
DPC DNA-protein crosslink
EAC esophageal adenocarcinoma
EGA European Genome–Phenome Archive
ESD S-formylglutathione hydrolase
EXO1 exonuclease 1
FA Fanconi anemia
FALDH fatty aldehyde dehydrogenase (ALDH3A2)
FANC Fanconi anemia complementation group
FISH fluorescence in situ hybridization
GABA γ-aminobutyric acid
GEO Gene Expression Omnibus
GLO1 glyoxalase 1
GLO2 glyoxalase 2 (also known as HAGH)
GSH glutathione
GSNO S-nitrosoglutathione
GSNOR S-nitrosoglutathione reductase (also known as ADH5)
GTEx Genotype-Tissue Expression
HAGH hydroxyacylglutathione hydrolase (also known as GLO2)
γH2AX phosphorylated H2A histone family member X
HNSCC head and neck squamous cell carcinoma
4-HNE 4-hydroxynonenal
HPV human papillomavirus
HR homologous recombination
HSC hematopoietic stem cell
HSPC hematopoietic stem and progenitor cell
IARC International Agency for Research on Cancer
ICL interstrand crosslink
iNOS inducible nitric oxide synthase
LC–MS liquid chromatography-mass spectrometry
MDA malondialdehyde
MG methylglyoxal
MGMT O6-methylguanine-DNA methyltransferase (also known as AGT)
MMR mismatch repair
MLH1 MutL homolog 1
MSH MutS homolog
MutLα MutL homolog complex (MLH1–PMS2)
MutSα MutS homolog complex (MSH2–MSH6)
NAD+ nicotinamide adenine dinucleotide
NER nucleotide excision repair
OGG1 8-oxoguanine DNA glycosylase 1
PARP poly(ADP-ribose) polymerase
PMS2 postmeiotic segregation increased 2
Polθ DNA polymerase theta
ROS reactive oxygen species
SCC squamous cell carcinoma
SHMT1/2 serine hydroxymethyltransferase 1/2
SLS Sjögren–Larsson syndrome
SOD superoxide dismutase
TARGET Therapeutically Applicable Research to Generate Effective Treatments
TCA tricarboxylic acid
TCGA The Cancer Genome Atlas
TLS translesion synthesis
TMEJ Polθ-mediated end joining
WT wildtype
XRCC1 X-ray repair cross-complementing 1