| ACS | Acute Chest Syndrome |
| AVN | Avascular Necrosis |
| CRISPR | Clustered Regularly Interspaced Short Palindromic Repeats |
| FDA | United States Food and Drug Administration |
| GVHD | Graft-Versus-Host Disease |
| HbA | Hemoglobin A (normal adult hemoglobin) |
| HbF | Fetal Hemoglobin |
| HbS | Hemoglobin S (sickle hemoglobin) |
| HBB | β-globin gene |
| HPFH | Hereditary Persistence of Fetal Hemoglobin |
| HSC | Hematopoietic Stem Cell |
| HSCT | Hematopoietic Stem Cell Transplantation |
| MHRA | Medicines and Healthcare products Regulatory Agency (UK) |
| NO | Nitric Oxide |
| PGD | Preimplantation Genetic Diagnosis |
| RBC | Red Blood Cell |
| ROS | Reactive Oxygen Species |
| SCD | Sickle Cell Disease |
| SCT | Sickle Cell Trait |
| VOC | Vaso-Occlusive Crisis |
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