| AFP | Alpha-fetoprotein |
| α-SMA | alpha-smooth muscle actin |
| CA125 | Carbohydrate antigen 125 |
| CA19-9 | Carbohydrate antigen 19-9 |
| CAF | Cancer-associated fibroblast |
| CCA | Cholangiocarcinoma |
| CEA | Carcinoembryonic antigen |
| ceRNA | Competitive endogenous RNA |
| circRNA | Circular RNA |
| COX-2 | Cyclooxygenase-2 |
| CSC | Cancer stem-like cell |
| CXCR4 | C-X-C chemokine receptor 4 |
| dCCA | Distal cholangiocarcinoma |
| eCCA | Extrahepatic cholangiocarcinoma |
| ECM | Extracellular matrix |
| EGF | Epidermal growth factor |
| EGFR | Epidermal growth factor receptor |
| EMT | Epithelial–mesenchymal transition |
| FGF | Fibroblast growth factor |
| FXR | Farnesoid X receptor |
| HCC | Hepatocellular carcinoma |
| HGF | Hepatocyte growth factor |
| HIF-1 | Hypoxia-inducible factor-1 |
| HRE | Hypoxia response element |
| iCCA | Intrahepatic cholangiocarcinoma |
| ICD | Immunogenic cell death |
| IHC | Immunohistochemistry |
| lncRNA | Long non-coding RNA |
| m6A | N6-methyladenosine |
| MAIT | Mucosal-associated invariant T |
| MDR1 | Multidrug resistance gene 1 |
| NGS | Next-generation sequencing |
| pCCA | Perihilar cholangiocarcinoma |
| PDGF | Platelet-derived growth factor |
| PSC | Primary sclerosing cholangitis |
| RTK | Receptor tyrosine kinase family |
| scRNA-seq | Single-cell RNA sequencing |
| ST | Spatial transcriptomics |
| TAM | Tumor-associated macrophage |
| TGF | Transforming growth factor |
| TME | Tumor microenvironment |
| TNF | Tumor necrosis factor |
| VEGF | Vascular endothelial growth factor |
| VEGFRs | VEGF receptors |