AAOS	American Academy of Orthopaedic Surgeons
ACR	American College of Rheumatology
BMI	body mass index
CAGR	compound annual growth rate
CDC	Centers for Disease Control and Prevention
CHECK	Cohort Hip and Cohort Knee study
CI	confidence interval
COPD	chronic obstructive pulmonary disease
COX-2	cyclooxygenase-2
CPRD	Clinical Practice Research Datalink
DDD	defined daily dose
EHR	electronic health record
EQ-5D	EuroQol 5-Dimension
EQ-5D-5L	EuroQol 5-Dimension 5-Level
ESCEO	European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
GBD	Global Burden of Disease
GDP	gross domestic product
HA	hyaluronic acid
HCRU	healthcare resource utilization
HIRA	Health Insurance Review and Assessment Service
HR	hazard ratio
HRQoL	health-related quality of life
HTO	high tibial osteotomy
IA-HA	intra-articular hyaluronic acid
ICER	incremental cost-effectiveness ratio
JPY	Japanese yen
KL	Kellgren–Lawrence grading scale
KOA	knee osteoarthritis
MCBS	Medicare Current Beneficiary Survey
MOST	Multicenter Osteoarthritis Study
NIS	National Inpatient Sample
NSAID	nonsteroidal anti-inflammatory drug
OA	osteoarthritis
OAI	Osteoarthritis Initiative
OAPol	Osteoarthritis Policy Model
OARSI	Osteoarthritis Research Society International
OR	odds ratio
OTC	over-the-counter
PPI	proton pump inhibitor
PRGF	plasma rich in growth factors
PRP	platelet-rich plasma
PT	physical therapy
QALY	quality-adjusted life year
RCT	randomized controlled trial
SF-6D	Short Form 6-Dimension
SKOA	symptomatic knee osteoarthritis
SYSADOA	symptomatic slow-acting drug for osteoarthritis
THA	total hip arthroplasty
TKA	total knee arthroplasty
TKR	total knee replacement
UK	United Kingdom
UKA	unicompartmental knee arthroplasty
US	United States
USD	United States dollar
WOMAC	Western Ontario and McMaster Universities Osteoarthritis Index
YLD	years lived with disability