ADCs	Antibody–drug conjugates
AF-HPA	Auristatin F hydroxypropylamide
Ala	Alanine
ALL	Acute lymphoblastic leukemia
AML	Acute myeloid leukemia
AzK	Nε-azido-lysine
AST	Advanced solid tumor
BC	Breast cancer
BCMs	B-cell malignancies
BCMA	B-cell maturation antigen
BCL	B-cell lymphoma
B-NHL	B-cell non-Hodgkin lymphoma
CLDN	Claudin
cGMP	Current good manufacturing practice
cGU	Cancer of genitourinary
Cit	Citrulline
CMC	Chemistry, manufacturing, and controls
CHO cells	Chinese hamster ovary cells
CRPC	Castration-resistant prostate cancer
CxCa	Cervical cancer
cUADT	Cancer of upper aerodi-gestive tract
DARs	Drug-to-antibody ratios
DLBCL	Diffuse large B-cell lymphoma
DM	Maytansinoid DM
Dxd	Deruxtecan
EC	Endometrial cancer
EGFR	Epidermal growth factor receptor
EOC	Epithelial ovarian cancer
EphA	Ephrin type-A receptor
ESC	Esophageal cancer
FcRn	Neonatal Fc receptor
FDA	Food and Drug Administration
FGE	Formylglycine-generating enzyme
FRα	Folate receptor alpha
GAC	Gastric adenocarcinoma
GC	Gastric cancer
GEJAC	Gastroesophageal junction adenocarcinoma
Gly	Glycine
HER2	Human epidermal growth factor receptor 2
HIC-HPLC	Hydrophobic interaction chromatography–high-performance liquid chromatography
HL	Hodgkin lymphoma
HR	Hormone receptor
LA/mAST	Locally advanced or metastatic solid tumors
LC	Lung cancer
LC–MS	Liquid chromatography–mass spectrometry
mAbs	Monoclonal antibodies
mBC	Metastatic breast cancer
MC	Maleimidocaproyl
mCC	Metastatic cervical cancer
mCRPC	Metastatic castration-resistant prostate cancer
MDS	Myelodysplastic syndrome
mGC	Metastatic gastric cancer
MM	Multiple myeloma
MMAE	Monomethyl auristatin E
mTG	Microbial transglutaminase
mTNBC	Metastatic triple-negative breast cancer
mUC	Metastatic urothelial carcinoma
NHS	N-hydroxysuccinimide
NSCLC	Non-small cell lung cancer
OC	Ovarian cancer
PABC	p-aminobenzyloxycarbonyl
pAcF	P-acetylphenylalanine
PC	Pancreatic cancer
PCD	Plasma cell disorders
PDAC	Pancreatic ductal adenocarcinoma
PEG	Polyethylene glycol
Phe	Phenylalanine
PROC	Platinum-resistant ovarian cancer
ROR1	Receptor tyrosine kinase-like orphan receptor 1
R/R	Relapsed/refractory
sALCL	Systemic anaplastic large cell lymphoma
SCLC	Small cell lung cancer
SEC	Size-exclusion chromatography
SMCC	Succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate
SPAAC	Strain-promoted azide–alkyne cycloaddition
Sulfo-SPDB	Sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
T-DXd	Trastuzumab deruxtecan
TNBC	Triple-negative breast cancer
Trop-2	Tumor-associated calcium signal transducer 2
UAA	Unnatural amino acid
UPC	Unresectable pancreatic cancer
Val	Valine