Table 1.
Patient characteristics by antidepressant prescription status upon discharge from acute stroke hospitalization.
| Antidepressant prescription on discharge |
||||
|---|---|---|---|---|
| Overall N = 803 | Yes N = 220 | No N = 583 | P-value | |
|
| ||||
| Age, mean ± SD | 62.7 ± 14.8 | 61.9 ± 14.6 | 63.0 ± 14.9 | 0.3546 |
| Sex, N (%) | 0.0031 | |||
| Male | 415 (51.7) | 95 (43.2) | 320 (54.9) | |
| Female | 388 (48.3) | 125 (56.8) | 263 (45.1) | |
| Race, N (%) | 0.1867 | |||
| White | 496 (61.8) | 144 (65.5) | 352 (60.4) | |
| Black | 307 (38.2) | 76 (34.6) | 231 (39.6) | |
| Tobacco use, N (%) | 0.2676 | |||
| Current | 218 (27.2) | 66 (30.0) | 152 (26.1) | |
| Former | 216 (26.9) | 63 (28.6) | 153 (26.2) | |
| Never | 369 (45.7) | 91 (41.4) | 278 (47.7) | |
| Alcohol use, N (%) | 0.2189 | |||
| Current | 265 (33.0) | 68 (30.9) | 197 (33.8) | |
| Former | 95 (11.8) | 33 (15.0) | 62 (10.6) | |
| Never | 443 (55.2) | 119 (54.1) | 324 (55.6) | |
| Clinical comorbidities, N (%) | ||||
| Number of comorbidities, mean ± SD | 2.7 ± 1.6 | 3.1 ± 1.8 | 2.5 ± 1.5 | <0.0001 |
| Hypertension | 596 (74.2) | 170 (77.3) | 426 (73.1) | 0.2247 |
| Diabetes | 232 (28.9) | 74 (33.6) | 158 (27.1) | 0.0684 |
| Dyslipidemia | 307 (38.2) | 93 (42.3) | 214 (36.7) | 0.1477 |
| Atrial fibrillation | 137 (17.1) | 36 (16.4) | 101 (17.3) | 0.7469 |
| Congestive heart failure | 81 (10.1) | 21 (9.6) | 60 (10.3) | 0.7542 |
| History of stroke/TIA | 225 (28.0) | 71 (32.3) | 154 (26.4) | 0.0993 |
| Coronary artery disease | 120 (14.9) | 39 (17.7) | 81 (13.9) | 0.1742 |
| Mental health variables, N (%) | ||||
| History of depression | 57 (7.1) | 39 (17.7) | 18 (3.1) | <0.0001 |
| Anxiety | 46 (5.7) | 29 (13.2) | 17 (2.9) | <0.0001 |
| Antidepressant use on admission | 456 (56.8) | 121 (55.0) | 335 (57.5) | 0.5300 |
| Stroke admission | ||||
| Admission NIHSS, median (IQR) | 4.0 (1.0, 11.0) | 5.0 (2.0, 12.5) | 4.0 (1.0, 10.0) | 0.0166 |
| Stroke type, N (%) | 0.9108 | |||
| Ischemic | 609 (75.8) | 165 (75.0) | 444 (76.2) | |
| Hemorrhagic | 110 (13.7) | 32 (14.6) | 78 (13.4) | |
| TIA/Other | 84 (10.5) | 23 (10.5) | 61 (10.5) | |
| Length of stay, median (IQR) | 2.0 (1.0, 4.0) | 4.0 (2.0, 9.0) | 3.0 (2.0, 7.0) | 0.0193 |
| Discharge disposition, N (%) | 0.0371 | |||
| Home | 484 (60.3) | 117 (53.2) | 367 (63.0) | |
| Rehabilitation facility | 205 (25.5) | 68 (30.9) | 137 (23.5) | |
| Other | 114 (14.2) | 35 (15.9) | 79 (13.6) | |
IQR, interquartile range; NIHSS, National Institutes of Health stroke scale; SD, standard deviation; TIA, transient ischemic attack.