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. Author manuscript; available in PMC: 2026 Jul 31.
Published in final edited form as: Int J Psychiatry Med. 2025 Jun 3;61(1):92–106. doi: 10.1177/00912174251348329

Table 2.

Factors associated with prevalence and initiation of antidepressant prescriptions at discharge.

Prevalent antidepressant prescriptions
Initiation of antidepressant
Crude
Multivariable
Multivariable
OR (95% CI) OR (95% CI) OR (95% CI)

Age 1.00 (0.99, 1.01) 0.99 (0.98, 1.01) 0.98 (0.97, 1.00)
Sex
 Male Referent Referent Referent
 Female 1.60 (1.17, 2.19) 1.53 (1.09, 2.16) 0.91 (0.55, 1.51)
Race
 White Referent Referent Referent
 Black 0.80 (0.58, 1.11) 0.67 (0.47, 0.96) 0.85 (0.51, 1.40)
Tobacco
 Never Referent Referent Referent
 Current 1.33 (0.91, 1.93) 1.38 (0.92, 2.10) 1.21 (0.67, 2.19)
 Former 1.26 (0.86, 1.83) 1.23 (0.81, 1.85) 1.25 (0.68, 2.30)
Alcohol
 Never Referent Referent Referent
 Current 0.94 (0.67, 1.33) 0.99 (0.68, 1.46) 0.87 (0.50, 1.52)
 Former 1.45 (0.90, 2.32) 1.56 (0.93, 2.63) 1.47 (0.71, 3.05)
Number of comorbidities 1.24 (1.13, 1.36) 1.16 (1.03, 1.32) 1.03 (0.85, 1.24)
Prior stroke/TIA 1.33 (0.95, 1.86) 0.89 (0.56, 1.35) 0.84 (0.44, 1.61)
History of depression 6.76 (3.78, 12.12) 4.91 (2.59, 9.31) 2.34 (0.79, 6.93)
Admission NIHSS 1.02 (1.00, 1.04) 1.02 (0.99, 1.04) 1.02 (0.98, 1.06)
Discharge disposition
 Home Referent Referent Referent
 Rehabilitation facility 1.56 (1.09, 2.23) 1.52 (1.01, 2.30) 2.92 (1.62, 5.28)
 Other 1.39 (0.89, 2.18) 1.39 (0.80, 2.42) 2.59 (1.17, 5.76)

CI, confidence interval; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; TIA, transient ischemic attack.

Multivariable model included age, sex, tobacco, alcohol, number of clinical comorbidities, prior stroke/TIA, history of depression, admission NIHSS, discharge disposition. Bold typeface indicates statistical significance.