FIG. 1.

Coactivator GT198. (A) Alignment of amino acid sequences of rat GT198 with human GT198 (44) and mouse GT198 (TBP-IP) (50). Amino acid variations between species are indicated. Identical amino acids (−) are indicated. The heptad repeats of leucine and methionine residues are shaded. (B) An α-helical wheel diagram for the leucine dimerization domain of rat GT198 (aa 86 to 117). Aligned leucines are at the d position, and hydrophobic residues are at the a position. (C) Gene structure of mouse GT198 on chromosome 11. Introns are shown as lines and exons are depicted as boxes. Coding regions are shown in black and noncoding regions are in white.