FIG. 5.

CD4⁺ memory phenotype T cells from CaMKIV^−/− mice display impaired immediate early gene induction. CD4⁺ memory phenotype T cells from wild-type and CaMKIV^−/− mice were stimulated with plate-bound CD3 and CD28 antibodies for 2 h. Total RNA was then isolated, and c-jun, fosB, fra2, and junB gene induction was determined by RT-PCR. The results of one representative experiment (n = 4) are shown.