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. 2002 Jan;22(1):117–126. doi: 10.1128/MCB.22.1.117-126.2002

FIG. 1.

FIG. 1.

IL-4-induced PI-3 kinase activity is reduced in IRS-2-deficient lymphocytes. Supernatants of homogenates from IL-4-treated and untreated splenocytes were immunoprecipitated with the indicated antibodies and assayed in vitro for PI-3 kinase activity. The results are expressed as fold stimulation of activity above untreated controls and are the average (+ standard deviation) of two independent experiments.