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. 2002 Aug 15;30(16):3624–3631. doi: 10.1093/nar/gkf469

Figure 4.

Figure 4

Relation of XPC intron 11 genotype to deletion of exon 12 in XPC mRNA and DNA repair function. (A) Real-time QRT–PCR was used to measure the amount of XPC mRNA deleting exon 12 and retaining exon 12. The proportion of deleted exon 12 XPC mRNA was significantly greater in cells with the A/A and A/C genotypes compared with the C/C genotype (the nine fibroblast lines assayed in duplicate are listed in Table 2). (B) Post-UV host cell reactivation was used to measure DNA repair function. The relative luciferase activity was significantly greater in the cells with the C/C genotype than in cells with the A/A genotype (the nine fibroblast lines assayed in triplicate are listed in Table 2).