Time-dependent fluctuations of the minor groove width, calculated using CURVES 5.1, of the central G-tract of methylphosphonate modified duplex, M_GGCC_ALT (top), and the unmodified duplex (bottom) at the (a) P6–P20, (b) P7–P19, (c) P8–P18 and (d) P9–P17 cross-strand groups over the entire simulation.