Table 6.

Comparisons of immunoglobulin replacement therapy

	Intravenous immunoglobulin	Subcutaneous immunoglobulin
Brand examples	Privigen®, Intragam Nexgen®	Hizentra®, Cuvitru®
Concentration	10%	20%
Route of administration	Intravenous	Subcutaneous
Frequency of administration	Every 4 weeks	Every 1–2 weeks
Duration of infusion	Shorter	Longer
Systemic adverse reactions	Higher	Fewer
Need for hospital visit	Yes, require medical personnel	No, self-administration at home
Need for patient and family training	No	Yes