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. 2026 Jul 17;5:e75561. doi: 10.2196/75561

Table 3.

Comparison between closed- and open-source vanilla models with zero-shot prompts.

Models Prompt Top 5 Top 10


F1-score (relaxed), mean (SD) F1-score (Jaccard), mean (SD) MRRa (SD), relaxed MRR (SD), Jaccard F1-score (relaxed), mean (SD) F1-score (Jaccard), mean (SD) MRR, SD (relaxed) MRR, SD (Jaccard)
Closed-source LLMs b

GPT-5.2


General 0.492 (0.068)c 0.307 (0.071) 0.578 (0.045)c 0.476 (0.124)c 0.496 (0.058)c 0.31 (0.077) 0.578 (0.045)c 0.467 (0.117)c


Structured 0.332 (0.077) 0.206 (0.048) 0.513 (0.153) 0.359 (0.123) 0.336 (0.073) 0.211 (0.047) 0.513 (0.153) 0.359 (0.123)

GPT-5-mini


General 0.46 (0.073) 0.129 (0.048) 0.561 (0.156) 0.196 (0.11) 0.505 (0.063) 0.145 (0.045) 0.552 (0.151) 0.196 (0.11)


Structured 0.387 (0.055) 0.12 (0.046) 0.575 (0.165) 0.24 (0.17) 0.387 (0.075) 0.127 (0.052) 0.566 (0.153) 0.24 (0.17)
Open-source LLMs

Mistral 7B


General 0.372 (0.085) 0.323 (0.081) 0.451 (0.175) 0.453 (0.172) 0.401 (0.119) 0.345 (0.115) 0.432 (0.167) 0.444 (0.177)


Structured 0.351 (0.083) 0.243 (0.056) 0.582 (0.108) 0.455 (0.112) 0.349 (0.081) 0.236 (0.055) 0.573 (0.106) 0.455 (0.112)

Llama 3.1 8B


General 0.347 (0.054) 0.333 (0.055) 0.426 (0.112) 0.392 (0.108) 0.368 (0.063) 0.35 (0.056) 0.422 (0.113) 0.392 (0.108)


Structured 0.371 (0.056) 0.188 (0.051) 0.521 (0.14) 0.318 (0.112) 0.358 (0.059) 0.186 (0.055) 0.517 (0.139) 0.318 (0.112)

BioMistral 7B


General 0.21 (0.076) 0.017 (0.032) 0.353 (0.141) 0.033 (0.071) 0.211 (0.078) 0.02 (0.04) 0.353 (0.141) 0.033 (0.071)


Structured 0.304 (0.121) 0.017 (0.018) 0.507 (0.152) 0.056 (0.056) 0.304 (0.123) 0.017 (0.018) 0.507 (0.152) 0.056 (0.056)

DeepSeek 8B


General 0.42 (0.077) 0.383 (0.053)c 0.416 (0.113) 0.398 (0.13) 0.443 (0.077) 0.409 (0.068)c 0.414 (0.113) 0.397 (0.13)


Structured 0.326 (0.026) 0.211 (0.053) 0.467 (0.131) 0.4 (0.158) 0.328 (0.048) 0.218 (0.059) 0.467 (0.131) 0.4 (0.158)

aMRR: mean reciprocal rank.

bHighest score for each metric (column) among the compared models.

cLLM: large language model.