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. Author manuscript; available in PMC: 2026 Aug 2.
Published in final edited form as: J Autoimmun. 2026 Jul 20;163:103597. doi: 10.1016/j.jaut.2026.103597

Figure 2. NC-TAC favors CD4 T cell regulatory phenotype in AIH.

Figure 2.

The frequency of CD4 T cells positive for FOXP3, RORC, IL-10, IL-17A and IFNγ was measured following treatment with NC, NC-TAC, TAC or vehicle by flow cytometry. Violin plots representing the frequency of (A) CD4+FOXP3+, (B) CD4+RORC+, (C) CD4+IL-10+, (D) CD4+IL-17A+ and (E) CD4+IFNγ+ cells following exposure to vehicle, NC, NC-TAC or TAC (HS, n=6-8; AIH, n=6-12). *P≤0.05; **P≤0.01 (one-way ANOVA test followed by Tukey’s multiple comparisons test). In each violin plot, median and quartiles are shown. NC-TAC imparts a regulatory phenotype to CD4 T cells of AIH patients.