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. 2026 Jul 20;14:1866750. doi: 10.3389/fcell.2026.1866750

FIGURE 2.

Line chart comparing GAIS scores over 12 months for Multipolar RF (study group, solid blue line) and Monopolar RF (control group, dashed orange line). Multipolar RF shows sustained higher mean scores and greater obvious improvement, with statistically significant differences at all time points.

Physician Global Aesthetic Improvement Scale (GAIS) Scores at Each Follow-Up Time Point by Treatment Group. Comparison of multipolar radiofrequency (study group) versus monopolar radiofrequency (control group) at 1, 3, 6, and 12 months post-treatment. Values represent mean ± standard deviation. Asterisks (*) denote statistically significant between-group differences at each time point (P < 0.001, Bonferroni-corrected). Both groups achieved peak aesthetic improvement at 3 months post-treatment.