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. 2026 Jul 20;14:1866750. doi: 10.3389/fcell.2026.1866750

TABLE 1.

Baseline characteristics of both groups.

Characteristic Study group (n = 42) Control group (n = 42)
Age (years, x̄±s) 43.8 ± 9.4 44.5 ± 8.7
Female, n (%) 35 (83.3%) 36 (85.7%)
BMI (kg/m2, x̄±s) 22.6 ± 2.8 22.9 ± 3.1
Fitzpatrick phototype III/IV, n (%) 38 (90.5%) 39 (92.9%)
Baseline R2 (%) 0.62 ± 0.08 0.61 ± 0.09
Prior cosmetic treatment, n (%) 0 (0%) 0 (0%)

All between-group comparisons P > 0.05 (independent samples t-test or chi-square test, as appropriate). Baseline skin laxity severity, comorbidity burden, and medication history also showed no significant between-group differences (data not shown).