Fig. 5.
Kinetics of dithionite-dependent reduction of monomeric CYP3A4 in solution containing Emulgen-913 at no substrate added (circles) and in the presence of 12 μM bromocriptine (squares) in linear (a) and semilogarithmic (b) coordinates. Lines show the results of fitting of the data to a mono-exponential equation. The buffer contained 0.15% Emulgen-913. Other conditions as indicated in Fig. 3.