Table 3.
Distribution of genes related to immune response, metabolic pathways, stress response and redox regulation, and oxidative stress defense in she-camels with and without metritis, emphasizing single nucleotide changes and their anticipated genetic effects.
| Gene | SNPs | Healthy n = 87 | Metritis n = 13 | Total n = 100 | Chi square value X2 | p value | kind of inherited change | Amino acid order and sort |
|---|---|---|---|---|---|---|---|---|
| CARD9 | T132C | 44/87 | −/13 | 44/100 | 11.7 | 0.002 | Synonymous | 44 Y |
| T251C | −/87 | 5/13 | 5/100 | 35.2 | 0.001 | Non- synonymous | 84 M to T | |
| SIGLEC1 | A181C | −/87 | 9/13 | 9/100 | 66.1 | 0.001 | Non- synonymous | 61 K to Q |
| VSIG4 | A164G | −/87 | 6/13 | 6/100 | 42.7 | 0.001 | Non- synonymous | 55 N to S |
| G406A | 37/87 | −/13 | 37/100 | 8.7 | 0.003 | Non- synonymous | 136 V to M | |
| BTRC | T51A | 53/87 | −/13 | 53/100 | 16.8 | 0.001 | Synonymous | 17 T |
| G195A | −/87 | 9/13 | 9/100 | 66.1 | 0.001 | Synonymous | 65 S | |
| A422G | 48/87 | −/13 | 48/100 | 13.7 | 0.001 | Non- synonymous | 141 K to R | |
| SLC2A3 | T63C | 59/87 | −/13 | 59/100 | 21.5 | 0.001 | Synonymous | 21 G |
| ACOD1 | G236T | 28/87 | −/13 | 28/100 | 5.8 | 0.01 | Non- synonymous | 79 R to L |
| CPT1A | T108C | −/87 | 7/13 | 7/100 | 50.3 | 0.001 | Synonymous | 36 V |
| C207T | 65/87 | −/13 | 65/100 | 27.7 | 0.001 | Synonymous | 69 D | |
| G246A | −/87 | 8/13 | 8/100 | 58.1 | 0.001 | Synonymous | 82 A | |
| PFKFB3 | A143C | −/87 | 11/13 | 11/100 | 82.7 | 0.001 | Non- synonymous | 48 D to A |
| ATF4 | C204A | −/87 | 8/13 | 8/100 | 58.1 | 0.001 | Synonymous | 68 G |
| GADD45B | T90C | −/87 | 9/13 | 9/100 | 66.1 | 0.001 | Synonymous | 30\u00B0C |
| SLC7A11 | A32G | 71/87 | −/13 | 69/100 | 36.5 | 0.001 | Non- synonymous | 11 N to S |
| G394A | 53/87 | −/13 | 53/100 | 16.8 | 0.001 | Non- synonymous | 132 V to I | |
| PRDX3 | T174A | 66/87 | −/13 | 66/100 | 29 | 0.001 | Non- synonymous | 58 D to T |
Caspase recruitment domain family member 9 (CARD9), sialic acid binding ig like lectin 1 (SIGLEC1), v-set and immunoglobulin domain containing 4 (VSIG4); beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC); solute carrier family 2 member 3 (SLC2A3), aconitate decarboxylase 1 (ACOD1), carnitine palmitoyltransferase 1a (CPT1A), 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3); activating transcription factor 4 (ATF4), growth arrest DNA damage inducible beta (GADD45B), solute carrier family 7 member 11 (SLC7A11); and peroxiredoxin 3 (PRDX3).