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Sample size needed to detect an absolute difference of 15% in the proportion of tranquillised patients (α = 5%, power = 80%).
| Haloperidol + promethazine (% tranquilised) | Midazolam (% tranquilised) | N |
| 5 | 20 | 152 |
| 10 | 25 | 200 |
| 15 | 30 | 242 |
| 20 | 35 | 276 |
| 25 | 40 | 304 |
| 30 | 45 | 326 |
| 35 | 50 | 340 |
