Table 3.

Effects of thiazolidinedione insulin sensitizers

↓	Insulin resistance
↓	Hyperinsulinemia
↓	Fasting blood sugar in type 2 diabetes mellitus
↓	Free fatty acids
↓	Triglycerides
↑	High-density lipoprotein cholesterol
↓	Plasminogen activator inhibitor-1 activity
↑	Vascular compliance
↓	Blood pressure/vascular resistance
↓	Macrophage inflammatory activity
Direct vascular effects

↑, increased; ↓, decreased