Table 3.
Risk factor distributions as measured prior to randomisation for men, women, high risk subjects with no history of vascular disease (Primary Prevention) and subjects with a history of vascular disease (Secondary Prevention). Data shown are mean (SD) for continuous variables and % of randomised subjects within each column for categorical variables.
| Men | Women | |||||
| Primary | Secondary | Primary | Secondary | |||
| Subjects (%) | 1345 (23.2) | 1459 (25.1) | 1894 (32.6) | 1106 (19.1) | ||
| Continuous variables | ||||||
| Age (years) | 74.7 (3.2) | 75.3(3.3) | 75.3 (3.3) | 76.2 (3.4) | ||
| SBP (mmHg) | 157.7 (21.7) | 152.8 (22.2) | 155.8 (21.3) | 151.5 (21.8) | ||
| DBP (mmHg) | 85.9 (11.4) | 81.9 (11.4) | 84.7 (11.2) | 82.1 (11.5) | ||
| Height (cm) | 172.5 (6.8) | 171.7 (6.6) | 159.1 (6.7) | 158.4 (6.6) | ||
| Weight (kg) | 79.1 (12.3) | 78.4 (11.6) | 68.9 (12.9) | 67.4 (12.1) | ||
| BMI (kg/m2) | 26.6 (3.8) | 26.6 (3.4) | 27.2 (4.7) | 26.9 (4.6) | ||
| Categorical variables | ||||||
| Smoking: | ||||||
| Current | 45.1 | 21.0 | 25.1 | 15.2 | ||
| Former | 39.3 | 60.9 | 24.9 | 35.2 | ||
| Never | 15.6 | 18.0 | 50.0 | 49.6 | ||
| Alcohol: | ||||||
| 0 units/week | 25.8 | 32.6 | 58.6 | 58.2 | ||
| 1–13 units/week | 47.9 | 43.6 | 36.5 | 38.3 | ||
| 14–20 units/week | 12.7 | 12.8 | 3.6 | 2.3 | ||
| > 20 units/week | 13.6 | 11.0 | 1.3 | 1.3 | ||
| History of: | ||||||
| Diabetes | 14.7 | 10.4 | 10.5 | 6.9 | ||
| Hypertension | 59.3 | 43.4 | 80.3 | 57.9 | ||
| Angina | 0 | 59.1 | 0 | 63.1 | ||
| Claudication | 0 | 16.0 | 0 | 14.2 | ||
| MI | 0 | 36.9 | 0 | 21.5 | ||
| Stroke | 0 | 9.4 | 0 | 9.0 | ||
| TIA | 0 | 16.8 | 0 | 18.1 | ||
| CABG | 0 | 9.1 | 0 | 2.1 | ||
| PTCA | 0 | 4.7 | 0 | 2.7 | ||
| PAD surgery | 0 | 5.9 | 0 | 3.4 | ||
| Medications | ||||||
| Beta Blockers | 19.6 | 28.8 | 26.6 | 28.6 | ||
| ACE-Inhibitors | 15.4 | 15.9 | 17.4 | 16.5 | ||
| A-II receptor antagonists | 1.6 | 1.2 | 2.9 | 2.0 | ||
| Diuretics | 32.3 | 28.1 | 53.3 | 45.7 | ||
| Calcium channel blockers | 18.4 | 34.3 | 17.6 | 34.0 | ||
| Nitrates | 0 | 41.7 | 0 | 43.6 | ||
| Aspirin/antiplatelets | 14.4 | 68.1 | 15.2 | 56.9 | ||
| Anti-coagulants | 0.7 | 4.9 | 0.3 | 2.4 | ||
| Other antihypertensives | 4.9 | 4.5 | 4.5 | 1.8 | ||
| Other anti-arrhythmic | 1.9 | 3.8 | 1.7 | 3.9 | ||
| Other anti-anginals | 0 | 1.3 | 0 | 1.8 | ||
| Blood glucose lowering: | ||||||
| insulin | 1.2 | 0.5 | 1.1 | 0.7 | ||
| oral hypoglycaemics | 7.4 | 6.7 | 6.5 | 3.4 | ||