Table 2.
TSD sequences are A-rich
TSD composition | Observed* | Expected† |
0-10% As | 0.1% | 2.7% |
10-20% As | 2.5% | 26.6% |
20-30% As | 8.6% | 23.8% |
30-40% As | 31.5% | 36.8% |
40-50% As | 18.0% | 7.4% |
50-60% As | 28.5% | 2.7% |
60-70% As | 5.2% | 0.1% |
Over 70% As | 5.5% | 0.0% |
*TSDs of length 15 nucleotides without mismatches were classified according to their A content. †Monte Carlo simulation was used to generate random 15-nucleotide sequences representative of the nucleotide population of the human genome. Only 10% of these randomly generated sequences were equal to or greater than the average A content of the TSDs.