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. 2026 Jun 26;65(14):2227–2249. doi: 10.1021/acs.biochem.6c00318

1. Area, Solvation Free Energy, and CSS of GRE Homodimer Interfaces.

PDB ID GRE Area (Å2) solvation free energy upon dimerization (kcal/mol) CSS (out of 1)
1H18 pyruvate formate lyase (PFL) 1900 –6.0 0.34
5BWE benzylsuccinate synthase (BSS) 1600 –12.0 1.0
1R9D glycerol dehydratase (GD) 1200 –8.3 0.66
2YAJ hydroxyphenylacetate decarboxylase (HPAD) 1800 –15.8 1.0