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. Author manuscript; available in PMC: 2026 Aug 8.
Published in final edited form as: Can J Ophthalmol. 2026 Feb 3;61(3):582–590. doi: 10.1016/j.jcjo.2025.12.017

Table 2.

Adjusted associations between patient characteristics and increase in cup-to-disc ratio

CDR increase ≥0.2
Baseline Variables Adjusted RR (95% CI)
Loss to follow-up:
Longest lapse between encounters
0 (had an encounter every year) Reference
1–2 years 1.01 (0.96, 1.07)
3–4 years 1.15 (1.00, 1.32)
Age (years)
<60 Reference
60–<70 1.01 (0.93, 1.09)
70–<80 1.24 (1.15, 1.34)
80+ 1.61 (1.49, 1.74)
Sex
Male 1.08 (1.04, 1.12)
Female Reference
Race
Asian Reference
Black or African American 1.06 (0.94, 1.21)
White 0.98 (0.87, 1.10)
Hispanic 1.07 (0.93, 1.22)
Native American and Alaska Native 0.65 (0.43, 0.95)
Native Hawaiian and Other Pacific Islander 0.86 (0.47, 1.44)
Insurance
Private Reference
Govt 1.31 (1.09, 1.57)
Medicaid 1.18 (1.00, 1.39)
Medicare FFS 1.28 (1.19, 1.37)
Medicare Managed 1.07 (0.98, 1.17)
Military 1.19 (0.86, 1.61)
Smoking status
Never Reference
Former 1.12 (1.08, 1.17)
Active 1.19 (1.12, 1.27)
Glaucoma severity
Mild Reference
Moderate 1.27 (1.13, 1.43)
Severe 1.05 (0.97, 1.13)
Unspecified 1.86 (1.61, 2.14)
IOP≥19 mmHg
Yes 1.17 (1.13, 1.22)
No Reference
CDR ≥0.70
Yes 0.23 (0.22, 0.25)
No Reference

CDR, cup-to-disc ratio; CI, confidence interval; FFS, fee for service; Govt, government (including the Indian Health Service and state-specific non-Medicaid plans); IOP, intraocular pressure; mmHg, millimeters mercury; RR, relative risk.