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. 2025 Dec 4;28(4):852–862. doi: 10.1007/s10903-025-01829-0

Table 5.

Participants’ knowledge of clinical trials (N = 52)

Variables Pre-test n (%) Post-test n (%)
CT1 tests new treatment for safety

 True

 False

 Not Available

31 (59.6%)

15 (28.8%)

6 (11.5%)

42 (80.8%)

4 (7.7%)

6 (11.5%)

Patient always receives the new treatment in a CT

 True

 False

 Not Available

23 (44.2%)

25 (48.1%)

4 (7.7%)

42 (80.8%)

5 (9.6%)

5 (9.6%)

Consent form explains CT risks

 True

 False

 Not Available

31 (59.6%)

16 (30.8%)

5 (9.6%)

41 (78.8%)

5 (9.6%)

6 (11.5%)

Must stay in CT until the doctor says otherwise

 True

 False

 Not Available

28 (53.8%)

20 (38.5%)

4 (7.7%)

18 (34.6%)

27 (51.9%)

7 (13.5%)

Experts and community review CT safety

 True

 False

 Not Available

44 (84.6%)

1 (1.9%)

7 (13.5%)

44 (84.6%)

1 (1.9%)

7 (13.5%)

CT assesses if treatment works

 True

 False

 Not Available

44 (84.6%)

4 (7.7%)

4 (7.7%)

47 (90.4%)

0 (0%)

5 (9.6%)

Treatment works the same for everyone

 True

 False

 Not Available

16 (30.8%)

30 (57.7%)

6 (11.5%)

6 (11.5%)

39 (75.0%)

7 (13.5%)

CT determine optimal medication doses

 True

 False

 Not Available

42 (80.8%)

6 (11.5%)

4 (7.7%)

44 (84.6%)

1 (1.9%)

7 (13.5%)

Joining CT is possible only if other options aren’t feasible

 True

 False

 Not Available

27 (51.9%)

19 (36.5%)

6 (11.5%)

22 (42.3%)

23 (44.2%)

7 (13.5%)

Potential benefit: access to new or better treatments

 True

 False

 Not Available

37 (71.2%)

9 (17.3%)

6 (11.5%)

45 (86.5%)

1 (1.9%)

6 (11.5%)

All side effects are known before trial starts

 True

 False

 Not Available

18 (34.6%)

28 (53.8%)

6 (11.5%)

22 (42.3%)

24 (46.2%)

6 (11.5%)

1Clinical trials