Skip to main content
PMC home page
Annals of Surgery logoLink to Annals of Surgery
. 1976 Oct;184(4):500–506. doi: 10.1097/00000658-197610000-00013

Parotid neoplasms: a report of 250 cases and review of the literature.

E J Dunn, T Kent, J Hines, I Cohn Jr
PMCID: PMC1345451  PMID: 1015893

Abstract

A 25-year experience with parotid tumors was reviewed. From a total of 250 neoplasms, 173 were histologically benign and 77 were malignant. Benign mixed tumors accounted for 59% of all lesions. Clinical parameters used to diagnose parotid neoplasms were found to be unreliable in determining whether a given tumor was benign or malignant. The mean age for malignant lesions was 10 years greater than for benign lesions. The phenomenon of malignant transformation of a benign tumor was considered in four patients. Complete surgical excision is the safest and preferred method for diagnosis. Preoperative needle or incisional biopsy are associated with a high degree of local recurrence. The appropriate management of any parotid tumor is predicated on special histological type. Local excision or enucleation no longer have a place in the surgical management of benign parotid tumors. Postoperative tumor recurrence and morbidity are directly related to awareness of surgical anatomy and pursuit of correct surgical techniques for adequate resection. The five-year recurrence rate for 102 benign mixed tumors was 6%. Recurrence in malignant tumors varied with specific histological types but was generally high. Five-year survival for all malignant parotid tumors was 48%.

Full text

PDF
501

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARIEL I. M., JEROME A. P., PACK G. T. Treatment of tumors of the parotid salivary gland. Surgery. 1954 Jan;35(1):124–158. [PubMed] [Google Scholar]
  2. BEAHRS O. H., ADSON M. A. The surgical anatomy and technic of parotidectomy. Am J Surg. 1958 Jun;95(6):885–896. doi: 10.1016/0002-9610(58)90831-6. [DOI] [PubMed] [Google Scholar]
  3. BEAHRS O. H., WOOLNER L. B., CARVETH S. W., DEVINE K. D. Surgical management of parotid lesions. Review of seven hundred sixty cases. Arch Surg. 1960 Jun;80:890–904. doi: 10.1001/archsurg.1960.01290230008002. [DOI] [PubMed] [Google Scholar]
  4. BEAHRS O. H., WOOLNER L. B., KIRKLIN J. W., DEVINE K. D. Carcinomatous transformation of mixed tumors of the parotid gland. AMA Arch Surg. 1957 Oct;75(4):605–614. doi: 10.1001/archsurg.1957.01280160115015. [DOI] [PubMed] [Google Scholar]
  5. Bardwill J. M. Tumors of the parotid gland. Am J Surg. 1967 Oct;114(4):498–502. doi: 10.1016/0002-9610(67)90005-0. [DOI] [PubMed] [Google Scholar]
  6. Baum R. K., Perzik S. L. Tumors of the parotid gland in children. Review of 40 cases. Am Surg. 1965 Nov;31(11):719–722. [PubMed] [Google Scholar]
  7. Beahrs O. H., Chong G. C. Management of the facial nerve in parotid gland surgery. Am J Surg. 1972 Oct;124(4):473–476. doi: 10.1016/0002-9610(72)90069-4. [DOI] [PubMed] [Google Scholar]
  8. CHAUDHRY A. P., GORLIN R. J. Papillary cystadenoma lymphomatosum (adenolymphoma); a review of the literature. Am J Surg. 1958 Jun;95(6):923–931. doi: 10.1016/0002-9610(58)90835-3. [DOI] [PubMed] [Google Scholar]
  9. Einstein R. A. Sialography in the differential diagnosis of parotid masses. Surg Gynecol Obstet. 1966 May;122(5):1079–1083. [PubMed] [Google Scholar]
  10. Evans J. C. Radiation therapy of salivary gland tumors. Radiol Clin Biol. 1966;35(3):153–191. [PubMed] [Google Scholar]
  11. FRAZELL E. L. Clinical aspects of tumors of the major salivary glands. Cancer. 1954 Jul;7(4):637–659. doi: 10.1002/1097-0142(195407)7:4<637::aid-cncr2820070403>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  12. Frazell E. L. Observations on the management of salivary gland tumors. CA Cancer J Clin. 1968 Jul-Aug;18(4):235–240. doi: 10.3322/canjclin.18.4.235. [DOI] [PubMed] [Google Scholar]
  13. Friedman E. W., Schwartz A. E. Diagnosis of salivary gland tumors. CA Cancer J Clin. 1974 Sep-Oct;24(5):266–273. doi: 10.3322/canjclin.24.5.266. [DOI] [PubMed] [Google Scholar]
  14. GRAGE T. B., LOBER P. H., ARHELGER S. W. Acinic cell carcinoma of the parotid gland. A clinicopathologic review of eleven cases. Am J Surg. 1961 Dec;102:765–768. doi: 10.1016/0002-9610(61)90581-5. [DOI] [PubMed] [Google Scholar]
  15. Gaisford J. C., Hanna D. C., Richardson G. S., Bindra R. N. Parotid tumors. Plast Reconstr Surg. 1969 May;43(5):504–510. doi: 10.1097/00006534-196905000-00009. [DOI] [PubMed] [Google Scholar]
  16. Garas J., Politis A., Besbeas S., Georgacas G., Papamatheakis J. Neoplasms of the parotid gland. Review of 185 operated cases. Int Surg. 1973 Mar;58(3):178–181. [PubMed] [Google Scholar]
  17. HANNA D. C., GAISFORD J. C. Parotid gland tumors. Diagnosis and treatment. Am J Surg. 1962 Nov;104:737–740. doi: 10.1016/0002-9610(62)90429-4. [DOI] [PubMed] [Google Scholar]
  18. Hanna D. C., Gaisford J. C., Richardson G. S., Bindra R. N. Tumors of the deep lobe of the parotid gland. Am J Surg. 1968 Oct;116(4):524–527. doi: 10.1016/0002-9610(68)90386-3. [DOI] [PubMed] [Google Scholar]
  19. Hoffman G. W. Parotid tumors. South Med J. 1967 Feb;60(2):113–118. doi: 10.1097/00007611-196702000-00001. [DOI] [PubMed] [Google Scholar]
  20. Hollander L., Cunningham M. P. Management of cancer of the parotid gland. Surg Clin North Am. 1973 Feb;53(1):113–119. doi: 10.1016/s0039-6109(16)39937-6. [DOI] [PubMed] [Google Scholar]
  21. Hugo N. E., McKinney P., Griffith B. H. Management of tumors of the parotid gland. Surg Clin North Am. 1973 Feb;53(1):105–111. doi: 10.1016/s0039-6109(16)39936-4. [DOI] [PubMed] [Google Scholar]
  22. KIRKLIN J. W., McDONALD J. R., HARRINGTON S. W., NEW G. B. Parotid tumors; histopathology, clinical behavior, and end results. Surg Gynecol Obstet. 1951 Jun;92(6):721–733. [PubMed] [Google Scholar]
  23. LaVenuta F., Flynn W. F., Moore J. A. Facial nerve paralysis secondary to benign parotid tumor. Arch Otolaryngol. 1969 Nov;90(5):603–604. doi: 10.1001/archotol.1969.00770030605014. [DOI] [PubMed] [Google Scholar]
  24. Lathrop F. D. Management of tumors of the parotid gland. Surg Clin North Am. 1967 Jun;47(3):589–594. doi: 10.1016/s0039-6109(16)38233-0. [DOI] [PubMed] [Google Scholar]
  25. Molnar L., Ranay P., Döbrössy L. Mixed tumours of the parotid gland. Oncology. 1971;25(2):143–162. doi: 10.1159/000224565. [DOI] [PubMed] [Google Scholar]
  26. PEACOCK E. E., Jr, BYARS L. T. Management of tumors of the parotid salivary gland. N C Med J. 1958 Jan;19(1):1–9. [PubMed] [Google Scholar]
  27. Perzik S. L., Fisher B. The place of neck dissection in the management of parotid tumors. Am J Surg. 1970 Sep;120(3):355–358. [PubMed] [Google Scholar]
  28. Richards G. J., Jr, Chambers R. G. Hydroxyurea in the treatment of neoplasms of the head and neck. A resurvey. Am J Surg. 1973 Oct;126(4):513–518. doi: 10.1016/s0002-9610(73)80041-8. [DOI] [PubMed] [Google Scholar]
  29. Spiro R. H., Huvos A. G., Strong E. W. Adenoid cystic carcinoma of salivary origin. A clinicopathologic study of 242 cases. Am J Surg. 1974 Oct;128(4):512–520. doi: 10.1016/0002-9610(74)90265-7. [DOI] [PubMed] [Google Scholar]
  30. Spiro R. H., Huvos A. G., Strong E. W. Cancer of the parotid gland. A clinicopathologic study of 288 primary cases. Am J Surg. 1975 Oct;130(4):452–459. doi: 10.1016/0002-9610(75)90483-3. [DOI] [PubMed] [Google Scholar]
  31. TURNER J. C., Jr, DEVINE K. D., JUDD E. S. The auriculotemporal (Frey) syndrome occurring after parotid surgery. Surg Gynecol Obstet. 1960 Nov;111:564–568. [PubMed] [Google Scholar]
  32. Thorvaldsson S. E., Beahrs O. H., Woolner L. B., Simons J. N. Mucoepidermoid tumors of the major salivary glands. Am J Surg. 1970 Oct;120(4):432–438. doi: 10.1016/s0002-9610(70)80002-2. [DOI] [PubMed] [Google Scholar]
  33. Woods J. E., Chong G. C., Beahrs O. H. Experience with 1,360 primary parotid tumors. Am J Surg. 1975 Oct;130(4):460–462. doi: 10.1016/0002-9610(75)90484-5. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES