Figure 9.

(a) Summary of the additional CREB4/CREB3 chimeric proteins. CH4 contains the C-terminal region of CREB4 fused to the N-terminal region of CREB3. The fusion junction was before the CREB4 TM domain. CH6 contained the lumenal domain of CREB3 fused to the N-terminal region of CREB4. The fusion junction was just after the S1P site of CREB4. (b) Cells were transfected, treated with brefeldin A (1 μg/ml; 8 h), or (d) contransfected with S1P and processed as described in legends to Figures 7 and 8.