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K5 Myc-transgenic tissue stains for markers of DNA double-strand breaks. Immunofluorescent staining was performed on skin sections from untreated wild-type mice, wild-type mice exposed to 3 Gy of IR 20 min before killing, K5 Myc mice, and K5 Myc, Atm-/- mice by using antibodies specific for ATM phosphorylated at serine-1981 (p-ATM), γH2AX, or SMC1 phosphorylated at serine-957 (p-SMC1).
