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. 2026 Jul 28;14:1909252. doi: 10.3389/fped.2026.1909252

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© 2026 Zhang, Lee, Annes, Zhang, Zhou, Qian and Deng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Four labeled Sanger sequencing chromatograms (A, B, C, D) display colored peaks representing nucleotide bases, with all showing the same gene region and a highlighted single nucleotide variant at position c.464A>G in the PTEN gene. — Sanger sequencing validation of PTEN c.464A > G (p.Tyr155Cys). (A) Patient (B) Patient's father (C) Patient's mother (D) Patient's older brother.