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. 2026 Jul 2;16(8):654. doi: 10.21037/qims-2025-1-2814

Table 1. Participant characteristics, laboratory tests, and cognitive assessment.

Variables T2DM-MCI (n=24) T2DM-nMCI (n=23) HCs (n=26) PFDR
Male 16 (66.7) 11 (47.8) 10 (38.5) 0.190a
Age (years) 60.0 [54.5, 62.0] 58.0 [46.0, 62.0] 53.5 [51.0, 61.3] 0.264c
Years of education 12 [12, 16] 16 [12, 16] 12 [12, 13] 0.190c
MoCA 22 [20, 25]†,‡ 26 [26, 27] 27 [26, 27] <0.001c
FBG (mmol/L) 7.75 [6.02, 11.17]‡ 7.45 [6.71, 8.86]‡ 5.04 [4.78, 5.45] <0.001c
HbA1c (mg/dL) 7.80±1.28‡ 7.35±1.30‡ 5.66±0.44 <0.001d
Disease duration (years) 13.0 [5.5, 20.0] 11.0 [7.0, 15.0] Null 0.840b

Data are presented as n (%), mean ± standard deviation or median [25th and 75th percentile]. †, compared to the T2DM-nMCI group, P<0.05; ‡, Compared to the HC group, P<0.05; a, Chi-squared test; b, Mann-Whitney U test; c, Kruskal-Wallis test; d, one-way ANOVA. ANOVA, analysis of variance; FBG, fasting blood glucose; FDR, false discovery rate; HbA1c, glycosylated hemoglobin; HCs, healthy controls; MoCA, Montreal cognitive assessment; T2DM-MCI, type 2 diabetes mellitus with mild cognitive impairment; T2DM-nMCI, type 2 diabetes mellitus without mild cognitive impairment.