Table 1. Participant characteristics, laboratory tests, and cognitive assessment.
| Variables | T2DM-MCI (n=24) | T2DM-nMCI (n=23) | HCs (n=26) | PFDR |
|---|---|---|---|---|
| Male | 16 (66.7) | 11 (47.8) | 10 (38.5) | 0.190a |
| Age (years) | 60.0 [54.5, 62.0] | 58.0 [46.0, 62.0] | 53.5 [51.0, 61.3] | 0.264c |
| Years of education | 12 [12, 16] | 16 [12, 16] | 12 [12, 13] | 0.190c |
| MoCA | 22 [20, 25]†,‡ | 26 [26, 27] | 27 [26, 27] | <0.001c |
| FBG (mmol/L) | 7.75 [6.02, 11.17]‡ | 7.45 [6.71, 8.86]‡ | 5.04 [4.78, 5.45] | <0.001c |
| HbA1c (mg/dL) | 7.80±1.28‡ | 7.35±1.30‡ | 5.66±0.44 | <0.001d |
| Disease duration (years) | 13.0 [5.5, 20.0] | 11.0 [7.0, 15.0] | Null | 0.840b |
Data are presented as n (%), mean ± standard deviation or median [25th and 75th percentile]. †, compared to the T2DM-nMCI group, P<0.05; ‡, Compared to the HC group, P<0.05; a, Chi-squared test; b, Mann-Whitney U test; c, Kruskal-Wallis test; d, one-way ANOVA. ANOVA, analysis of variance; FBG, fasting blood glucose; FDR, false discovery rate; HbA1c, glycosylated hemoglobin; HCs, healthy controls; MoCA, Montreal cognitive assessment; T2DM-MCI, type 2 diabetes mellitus with mild cognitive impairment; T2DM-nMCI, type 2 diabetes mellitus without mild cognitive impairment.