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. 2026 Jun 8;26:689. doi: 10.1186/s12872-026-05971-x

Table 4.

Absolute differences between the standard 12-lead and handheld 6-lead ECGs under different acquisition conditions

Supine position
Metric N  < 5 5 ≤ < 10  ≥ 10
Heart rate (bpm) 107 107 (100.0%) 0 (0.0%) 0 (0.0%)
 < 20 20 ≤ < 40  ≥ 40
PR interval (ms) 63 45 (71.4%) 16 (25.4%) 2 (3.2%)
QRS duration (ms) 107 81 (75.7%) 26 (24.3%) 0 (0.0%)
QT interval (ms) 107 61 (57.0%) 35 (32.7%) 11 (10.3%)
QTc interval (ms) 107 57 (53.3%) 33 (30.8%) 17 (15.9%)
 < 0.05 0.05 ≤ < 0.1  ≥ 0.1
P amplitude (mV) 63 45 (71.4%) 14 (22.2%) 4 (6.4%)
QRS amplitude (mV) 107 55 (51.4%) 28 (26.2%) 24 (22.4%)
T amplitude (mV) 107 79 (73.8%) 26 (24.3%) 2 (1.9%)
Sitting position
Metric N  < 5 5 ≤ < 10  ≥ 10
Heart rate (bpm) 109 107 (98.2%) 2 (1.8%) 0 (0.0%)
 < 20 20 ≤ < 40  ≥ 40
PR interval (ms) 61 43 (70.5%) 17 (27.9%) 1 (1.6%)
QRS duration (ms) 109 80 (73.4%) 29 (26.6%) 0 (0.0%)
QT interval (ms) 109 67 (61.5%) 30 (27.5%) 12 (11.0%)
QTc interval (ms) 109 60 (55.1%) 33 (30.3%) 16 (14.7%)
 < 0.05 0.05 ≤ < 0.1  ≥ 0.1
P amplitude (mV) 61 50 (82.0%) 10 (16.4%) 1 (1.6%)
QRS amplitude (mV) 109 56 (51.4%) 32 (29.4%) 21 (19.3%)
T amplitude (mV) 109 74 (67.9%) 29 (26.6%) 6 (5.5%)
Asynchronous pairs
Metric N  < 5 5 ≤ < 10  ≥ 10
Heart rate (bpm) 96 44 (45.8%) 26 (27.1%) 26 (27.1%)
 < 20 20 ≤ < 40  ≥ 40
PR interval (ms) 54 29 (53.7%) 18 (33.3%) 7 (13.0%)
QRS duration (ms) 96 66 (68.8%) 23 (24.0%) 7 (7.3%)
QT interval (ms) 96 46 (47.9%) 31 (32.3%) 19 (19.8%)
QTc interval (ms) 96 33 (34.4%) 28 (29.2%) 35 (36.5%)
 < 0.05 0.05 ≤ < 0.1  ≥ 0.1
P amplitude (mV) 54 37 (68.5%) 10 (18.5%) 7 (13.0%)
QRS amplitude (mV) 96 22 (22.9%) 24 (25.0%) 50 (52.1%)
T amplitude (mV) 96 54 (56.3%) 22 (22.9%) 20 (20.8%)

For asynchronous analysis, non-simultaneous ECGs were matched post hoc by pairing a supine 12-lead ECG with a sitting 6-lead ECG from the same patient. The comparisons were restricted to pairs with consistent rhythm classifications for both devices. Rhythms that may be affected by premature complexes (APC and VPC) were grouped into the sinus rhythm categories. Cases without identifiable P waves were excluded from PR interval and P amplitude analyses

ECG electrocardiogram, bpm beats per minute, ms milliseconds, mV millivolts