Table 5.
Antiviral counter-screen against pVSV and pH5N1 by compounds 35 and 41.
| Compound | pEBOV EC50 (μM) | pMARV EC50 (μM) | pVSV-G EC50 (μM) | pH5N1 EC50 (μM) |
|---|---|---|---|---|
| 35 | 0.026 ± 0.005 | 0.44± 0.1 | 11.7 ± 0.2 | 24.8 ± 7.0 |
| 41 | 0.040 ± 0.002 | 0.42±0.03 | 10.2 ± 1.0 | 11.3 ± 0.6 |