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. Author manuscript; available in PMC: 2026 Aug 13.
Published in final edited form as: J Med Chem. 2026 Aug 13;69(15):18025–18050. doi: 10.1021/acs.jmedchem.6c00260

Table 5.

Antiviral counter-screen against pVSV and pH5N1 by compounds 35 and 41.

Compound pEBOV EC50 (μM) pMARV EC50 (μM) pVSV-G EC50 (μM) pH5N1 EC50 (μM)
35 0.026 ± 0.005 0.44± 0.1 11.7 ± 0.2 24.8 ± 7.0
41 0.040 ± 0.002 0.42±0.03 10.2 ± 1.0 11.3 ± 0.6