Appendix A1.

Co-existing conditions of the study subjects.

Comorbidities	N (%)
Neurologic
Developmental Delay	109 (51)
Learning difficulties	59 (28)
Behavioral concerns	46 (22)
Brain malformations	47 (22)
Cerebral palsy	43 (20)
Psychiatric diagnoses	41 (19)
Acquired brain injury	34 (16)
Respiratory
Obstructive sleep apnea	22 (10)
Asthma	18 (8)
Chronic lung disease	12 (6)
Ventilator dependence	6 (3)
Prematurity	24 (11)
Gastrointestinal	16 (8)
Endocrine	15 (7)
Renal	8 (4)
Hematologic/Oncologic	4 (2)
Immune	2 (1)

Medical comorbidities recorded for each patient. An individual patient may have more than one comorbidity.