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. Author manuscript; available in PMC: 2026 Aug 13.
Published in final edited form as: Obesity (Silver Spring). 2025 Nov 21;34(2):482–490. doi: 10.1002/oby.70076

Table 1.

Baseline characteristics of individuals with 3 months of continuous GLP-1 use for intention-to-treat analyses (n=78,076).

Characteristics Total
(n=78,076)
Continuous users
(n=48,956)
Discontinuous
Users
(n=29,120)
SMD
Age (mean, standard deviation) 54.3 (±13.5) 54.2 (±13.4) 54.4 (±13.6) 0.019
Sex, % 0.020
 Female 64.3% 64.7% 63.7%
 Male 35.7% 35.3% 36.3%
Race, %
 White 65.2% 66.6% 62.8% −0.080
 Black or African American 20.1% 19.0% 21.8% 0.070
 Asian 3.1% 3.2% 3.0% −0.010
 Native Hawaiian or Other Pacific Islander 0.8% 0.8% 0.9% 0.010
 American Indian or Alaska Native 0.5% 0.5% 0.5% −0.005
 Other race 4.0% 3.8% 4.3% 0.024
 Unknown 6.3% 6.0% 6.7% 0.028
Ethnicity, %
 Hispanic or Latino 10.9% 11.4% 10.1% −0.043
 Not Hispanic or Latino 78.2% 79.7% 75.6% −0.099
 Unknown 10.9% 8.9% 14.3% 0.170
Marital status, %
 Married 36.5% 36.1% 37.2% 0.022
 Single 25.0% 24.6% 25.8% 0.029
 Unknown 38.5% 39.3% 37.0% −0.048
Regional location, %
 Northeast 12.5% 10.7% 15.6% 0.146
 Midwest 27.0% 27.6% 25.9% −0.040
 South 46.4% 47.5% 44.6% −0.058
 West 14.1% 14.2% 13.9% −0.009
CCI (mean, standard deviation) 2.6 (±3.0) 2.7 (±3.1) 2.4 (±2.8) −0.100
Diabetes, % 65.8% 65.2% 66.7% 0.032
Medication, %
 Metformin 44.4% 45.8% 42.0% −0.077
 Sulfonylureas 17.8% 18.6% 16.6% −0.050
 DPP-4 inhibitors 11.8% 12.4% 10.9% −0.046
 SGLT2 inhibitors 11.4% 11.4% 11.4% −0.000
 Insulin 30.6% 30.6% 30.5% −0.002

CCI Charlson Comorbidity Index; SMD standardized mean difference