FIG. 1.

RhoH is a hematopoiesis-specific gene. (a) Expression in cell lines. RhoH is expressed at high levels in T (Jurkat) and B (Raji) cell lines and at low levels in the mixed lymphoid-erythroid line BaF3. In myeloid (HL60 and U937) and erythroid (K562) cell lines, RhoH is not detectable. All nonhematopoietic cells lines, including undifferentiated embryonal stem (ES) cells, are negative for RhoH. (b) Expression in tissues. mRNA was seen at high levels in the thymus, was less abundant in the spleen, and was lowest in abundance in bone marrow. In all other tissues, RhoH mRNA was nondetectable.