| AD | Alzheimer’s Disease |
| AID | Activation-Induced Cytidine Deaminase |
| ALS | Amyotrophic Lateral Sclerosis |
| AML | Acute Myeloid Leukemia |
| ARE | AU-Rich Element |
| ARS2 | Arsenite Resistance Protein 2 (SRRT) |
| ATF7IP | Activating Transcription Factor 7-Interacting Protein |
| ATRX | Alpha Thalassemia/Mental Retardation Syndrome X-Linked |
| C1D | C1D Nuclear Receptor Co-repressor (Rrp47) |
| CBCA | Cap-Binding Complex-ARS2 |
| CBX1 | Chromobox Protein Homolog 1 (HP1β) |
| CBX3 | Chromobox Protein Homolog 3 (HP1γ) |
| CBX5 | Chromobox Protein Homolog 5 (HP1α) |
| CDK13 | Cyclin-Dependent Kinase 13 |
| cenRNA | Centromeric RNA |
| cGAMP | Cyclic GMP-AMP |
| cGAS | Cyclic GMP-AMP Synthase |
| ChIP-seq | Chromatin Immunoprecipitation Sequencing |
| CMT | Charcot-Marie-Tooth Disease |
| cPcdh | Clustered Protocadherin |
| CRISPR | Clustered Regularly Interspaced Short Palindromic Repeats |
| cryo-EM | Cryogenic Electron Microscopy |
| CSR | Class-Switch Recombination |
| CTCF | CCCTC-Binding Factor |
| CUT | Cryptic Unstable Transcript |
| daRNA | Downstream Antisense RNA |
| DIS3 | Dis3 Homolog, Exosome Endoribonuclease and 3′→5′ Exoribonuclease |
| DIS3L | DIS3-Like Exoribonuclease 1 |
| DIS3L2 | DIS3-Like Exoribonuclease 2 |
| DNMT | DNA Methyltransferase |
| dsRNA | Double-Stranded RNA |
| EHMT1 | Euchromatic Histone Lysine Methyltransferase 1 (GLP) |
| eRNA | Enhancer RNA |
| ERV | Endogenous Retrovirus |
| ESC | Embryonic Stem Cell |
| Exo-9 | Nine-Subunit Exosome Core |
| FTD | Frontotemporal Dementia |
| FTLD | Frontotemporal Lobar Degeneration |
| H3K27me3 | Histone H3 Lysine 27 Trimethylation |
| H3K4me3 | Histone H3 Lysine 4 Trimethylation |
| H3K9me2 | Histone H3 Lysine 9 Dimethylation |
| H3K9me3 | Histone H3 Lysine 9 Trimethylation |
| HCC | Hepatocellular Carcinoma |
| HERVL | Human Endogenous Retrovirus L |
| HP1 | Heterochromatin Protein 1 |
| HUSH | Human Silencing Hub |
| IAP | Intracisternal A-Particle |
| IBD | Inflammatory Bowel Disease |
| IFN | Interferon |
| iPSC | Induced Pluripotent Stem Cell |
| IRF2 | Interferon Regulatory Factor 2 |
| ISG | Interferon-Stimulated Gene |
| KAP1 | KRAB-Associated Protein 1 (TRIM28) |
| KRAB-ZFP | Krüppel-Associated Box Zinc Finger Protein |
| LINE-1 | Long Interspersed Nuclear Element 1 |
| lncRNA | Long Noncoding RNA |
| LTR | Long Terminal Repeat |
| m6A | N6-Methyladenosine |
| MAVS | Mitochondrial Antiviral-Signaling Protein |
| MDA5 | Melanoma Differentiation-Associated Protein 5 |
| MERVL | Mouse Endogenous Retrovirus L |
| MiCEE | Mirlet7d-C1D-Exosome-EXOSC10 Complex |
| MM | Multiple Myeloma |
| MORC2 | MORC Family CW-Type Zinc Finger 2 |
| MPP6 | M-Phase Phosphoprotein 6 |
| MPP8 | M-Phase Phosphoprotein 8 (MPHOSPH8) |
| mRNA | Messenger RNA |
| MTR4 | mRNA Transport 4 (DExH-box RNA Helicase) |
| ncRNA | Noncoding RNA |
| NEXT | Nuclear Exosome-Targeting Complex |
| OPMD | Oculopharyngeal Muscular Dystrophy |
| PABPC1 | Poly(A)-Binding Protein Cytoplasmic 1 |
| PABPN1 | Poly(A)-Binding Protein Nuclear 1 |
| PAXT | Poly(A) Tail Exosome-Targeting Connection |
| Pcdh | Protocadherin |
| PCH | Pontocerebellar Hypoplasia |
| Pol II | RNA Polymerase II |
| PRC2 | Polycomb Repressive Complex 2 |
| PROMPT | Promoter Upstream Transcript |
| R-loop | RNA:DNA Hybrid with Displaced Single-Stranded DNA |
| RAN | Repeat-Associated Non-AUG Translation |
| RBM7 | RNA-Binding Motif Protein 7 |
| RIG-I | Retinoic Acid-Inducible Gene I |
| rRNA | Ribosomal RNA |
| SASP | Senescence-Associated Secretory Phenotype |
| SETDB1 | SET Domain Bifurcated Histone Lysine Methyltransferase 1 |
| SHM | Somatic Hypermutation |
| SHRF | Short Stature, Hearing Loss, Retinitis Pigmentosa, and Distinctive Facies |
| SKI | Superkiller Complex |
| SKIV2L | Superkiller Viralicidic Activity 2-Like |
| SMA | Spinal Muscular Atrophy |
| snoRNA | Small Nucleolar RNA |
| snRNA | Small Nuclear RNA |
| STING | Stimulator of Interferon Genes |
| SVA | SINE-VNTR-Alu Retrotransposon |
| TAD | Topologically Associating Domain |
| TASOR | Transgene Activation Suppressor (FAM208A) |
| TASOR2 | TASOR Paralog (FAM208B) |
| TE | Transposable Element |
| TERC | Telomerase RNA Component |
| THES | Trichohepatoenteric Syndrome |
| TRAMP | Trf4/5-Air1/2-Mtr4 Polyadenylation Complex |
| TREX1 | Three Prime Repair Exonuclease 1 |
| TRIM28 | Tripartite Motif-Containing 28 |
| TTC37 | Tetratricopeptide Repeat Domain 37 (SKI3/Thespin) |
| WAPL | Wings Apart-Like Protein Homolog |
| YTHDC1 | YTH Domain-Containing Protein 1 |
| ZC3H18 | Zinc Finger CCCH-Type Containing 18 |
| ZCCHC8 | Zinc Finger CCHC-Type Containing 8 |
| ZFC3H1 | Zinc Finger C3H1-Type Containing |