| AUC-ROC | Area under the receiver operating characteristic curve |
| BH | Benjamini–Hochberg |
| CJD | Creutzfeldt–Jakob disease |
| CpG | Cytosine–phosphate–guanine |
| DEG | Differentially expressed gene |
| DEF | Differentially expressed feature |
| DMR | Differentially methylated region |
| FDR | False discovery rate |
| FDR-BH | Benjamini–Hochberg false discovery rate correction |
| FET | Fisher’s exact test |
| GEO | Gene Expression Omnibus |
| GO-BP | Gene Ontology Biological Process |
| GRCh38 | Genome Reference Consortium Human Build 38 |
| GSEA | Gene set enrichment analysis |
| LOOCV | Leave-one-out cross-validation |
| MSigDB | Molecular Signatures Database |
| NES | Normalized enrichment score |
| PCA | Principal component analysis |
| PR-AUC | Precision–recall area under the curve |
| PrP | Prion protein |
| PrP^C | Cellular prion protein |
| sCJD | Sporadic Creutzfeldt–Jakob disease |
| SNP | Single-nucleotide polymorphism |
| YAML | YAML Ain’t Markup Language |