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. 2026 Aug 4;18(15):2497. doi: 10.3390/cancers18152497
5-FU 5-fluorouracil
ACT adoptive cell therapy
AGO2 argonaute RISC catalytic component 2
APC antigen-presenting cell
ApoE apolipoprotein E
ASGR asialoglycoprotein receptor
ASO antisense oligonucleotide
ATG3 Autophagy-related 3
AUNP gold nanoparticle
BC bladder cancer
BCL2 B-cell lymphoma 2
BCL-XL B-cell lymphoma extra-large
BRCA breast cancer
CAF cancer-associated fibroblast
cAMP cyclic AMP
CAR-T chimeric antigen receptor T-cell
CDX cell line-derived xenograft
ceRNA competing endogenous RNA
CLL chronic lymphocytic leukemia
c-MET c-mesenchymal–epithelial transition
CRC colorectal cancer
CRISPRi CRISPR interference
CTCL cutaneous T-cell lymphoma
CXCL12 C-X-C motif chemokine ligand 12
DDR DNA damage response
DECR1 2,4-dienoyl-CoA reductase 1
DNA-PKcs DNA-dependent protein kinase catalytic subunit
DNMT DNA methyltransferase
DOK1 downstream of tyrosine kinase 1
DOPC 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine
DOTAP 1,2-dioleoyl-3-dimethylammonium-propane
dsRNA double-stranded RNA
EGFR epidermal growth factor receptor
EMA European Medicines Agency
EMT Epithelial-to-mesenchymal transition
EV extracellular vesicles
FAO fatty acid oxidation
FDA Food and Drug Administration
GalNAc N-acetylgalactosamine
GC gastric cancer
GPCR G-protein-coupled receptor
GPCR-Gαi G protein-coupled receptor-inhibitory alpha (α) subunit of the G protein
GSH glutathione
HCC hepatocellular carcinoma
HER2 human epidermal growth factor receptor 2
HGF hepatocyte growth factor
HIF-1α hypoxia-inducible factor 1 alpha
HMGA1 high mobility group A1
HNSCC head and neck squamous cell carcinoma
Hsp27 heat shock protein 27
hTR Human telomerase RNA
HuR Hu antigen R
ICI immune checkpoint inhibitor
IFN type I interferon
KIRC kidney renal clear cell carcinoma
LIHC liver hepatocellular carcinoma
LNA locked nucleic acid
lncRNA long non-coding RNA
LNP lipid nanoparticle
m6A N6-methyladenosine
mAb monoclonal antibody
MCM3 Minichromosome Maintenance Complex 3
MDM2 mouse double minute 2 homolog
METTL3 methyltransferase-like 3
MHC-I major histocompatibility complex class I
miRNA microRNA
MMP matrix metalloproteinase
mRNA messenger RNA
ncRNA non-coding RNA
NHEJ non-homologous end joining
N-HER2 nuclear human epidermal growth factor receptor 2
NPC nasopharyngeal carcinoma
NSCLC non-small-cell lung cancer
OE Overexpressed
PAK5 p21-activated kinase 5
PCBP1 Poly(rC)-binding protein 1
PD-1 programmed cell death protein 1
PDAC pancreatic ductal adenocarcinoma
PD-L1/2 programmed cell death ligand 1 or 2
PDX patient-derived xenograft
PEG polyethylene glycol
PEI Polyethylenimine
PHD2 prolyl hydroxylase domain protein 2
PIP3 phosphatidylinositol-(3,4,5)-triphosphate
PKA protein kinase A
PKN3 protein kinase N3
PLC Peptide-Loading Components (not to be mistaken with phospholipase C)
PLGA poly(lactide-co-glycolactide)
PPARα peroxisome proliferator-activated receptor alpha
PUFA polyunsaturated fatty acid
RISC RNA-induced silencing complex
ROS reactive oxygen species
SELEX systemic evolution of ligands by exponential enrichment
siRNA small interfering RNA
SMKI small molecule kinase inhibitor
SORT selective organ-targeting
ssDNA single-stranded DNA
ssRNA single-stranded RNA
TAM tumor-associated macrophage
TCR T-cell receptor
TLR Toll-like receptor
TNBC triple negative breast cancer
TNS4 tension focal adhesion 4
TTR transthyretin
UE Underexpressed
WT1 Wilms’ Tumor 1 protein
YTHDC1 YTH domain-containing protein 1
YTHDF3 YTH N6-methyladenosine RNA-binding protein 3