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. 2026 Jul 25;18(15):2395. doi: 10.3390/cancers18152395
A549 Human lung adenocarcinoma cell line
AKT Protein kinase B
AKT1 AKT serine/threonine kinase 1
As Arsenic
ATSDR Agency for Toxic Substances and Disease Registry
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell lymphoma 2
BEAS-2B Human bronchial epithelial cell line
c-IAP2 Cellular inhibitor of apoptosis protein 2
CAT Catalase
CCNB1 Cyclin B1
Cd Cadmium
Cl1-0 Human lung invasive cancer cell line
Cr(VI) Hexavalent chromium
CTD Comparative Toxicogenomics Database
DNA Deoxyribonucleic acid
EGFR Epidermal growth factor receptor
ERK1/2 Extracellular signal-regulated kinase 1/2
ErbB ErbB family of receptor tyrosine kinases
FAK Focal adhesion kinase
FOS Fos proto-oncogene
G:C Guanine:cytosine
T:A Thymine:adenine
GPX1 Glutathione peroxidase 1
GPX3 Glutathione peroxidase 3
GSTM1 Glutathione S-transferase Mu 1
H125 Human lung cancer cell line
HIF-1 Hypoxia-inducible factor 1
HIF-1α Hypoxia-inducible factor 1 alpha
HIF1A Hypoxia-inducible factor 1 subunit alpha
HMOX1 Heme oxygenase 1
IARC International Agency for Research on Cancer
IFNG Interferon gamma
IL1B Interleukin 1 beta
IL4 Interleukin 4
IL6 Interleukin 6
IL13 Interleukin 13
Integrin β3 Integrin beta 3
JAK Janus kinase
JNK c-Jun N-terminal kinase
KRAS KRAS proto-oncogene
MAPK Mitogen-activated protein kinase
MAPK1 Mitogen-activated protein kinase 1
MAPK3 Mitogen-activated protein kinase 3
MeHgCl Methylmercury chloride
MMC Methylmercury compounds
mRNA Messenger ribonucleic acid
mTOR Mechanistic target of rapamycin
MSP Macrophage-stimulating protein
MTOR Mechanistic target of rapamycin kinase
MyD88 Myeloid differentiation primary response protein 88
NF-κB Nuclear factor kappa B
Ni Nickel
NNK 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
NOS2 Nitric oxide synthase 2
NQO1 NAD(P)H quinone dehydrogenase 1
NSCLC Non-small-cell lung cancer
OGG1 8-Oxoguanine DNA glycosylase 1
P70S6K 70 kDa ribosomal protein S6 kinase
PARP Poly(ADP-ribose) polymerase
Pb Lead
PD-L1 Programmed death-ligand 1
PI3K Phosphoinositide 3-kinase
PRKN Parkin RBR E3 ubiquitin protein ligase
PTEN Phosphatase and tensin homolog
p38 MAPK p38 mitogen-activated protein kinase
p53 Tumor protein p53
p21 Cyclin-dependent kinase inhibitor 1A
RB1 RB transcriptional corepressor 1
RAS Rat sarcoma viral oncogene homolog
RAF Rapidly accelerated fibrosarcoma kinase
RON Recepteur d’origine nantais (macrophage-stimulating 1 protein receptor)
ROS Reactive oxygen species
RTK Receptor tyrosine kinase
SCLC Small-cell lung cancer
SOD2 Superoxide dismutase 2
SOX2 SRY-box transcription factor 2
STAT3 Signal transducer and activator of transcription 3
STAT6 Signal transducer and activator of transcription 6
TGF-β Transforming growth factor beta
TLR4 Toll-like receptor 4
TNF Tumor necrosis factor
TP53 Tumor protein p53
VEGF Vascular endothelial growth factor
VEGFA Vascular endothelial growth factor A
VEGFR Vascular endothelial growth factor receptor
WHO World Health Organization
(GT)n Guanine–thymine dinucleotide repeat